Program
To access the videos, click on the blue names
THURSDAY 12th JANUARY
8.00 am – WELCOMING
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8.30 am – INTRODUCTION OF THE DAY
◗ Françoise Jeanson, Vice President of Health and Silver Economy of the Regional Council of New Aquitaine
Elected representative of the health, health and social training commission of Régions de France
◗ Nadine Houédé, Director of the Cancéropôle Grand Sud-Ouest
◗ Pierre Soubeyran, Director of the Oncosphère Nouvelle-Aquitaine
9.00 am – EXPOSOME
Chairwomen:
Angéline Galvin and Isabelle Baldi
How it could be measured in epidemiological studies on human health, the example of pesticides?
◗ Pierre Lebailly, Senior Lecturer in Public Health Inserm, UMR 1086 ANTICIPE, INSERM Université de Caen Normandie, Centre de Luttre Contre le Cancer François Baclesse, Caen, France
Pesticides exposure in fruit-growers: results from the CANEPA study
◗ Mathilde Bureau, Agronomist, Project manager Université de Bordeaux, BPH INSERM U1219, équipe EPICENE
REALYSA cohort: example of PELyCAnO projet « Pesticide Exposome,Lymphomagenesis, Chemoresistance and survival Outcomes »
◗ Sandra le Guyader Peyrou, Epidemiologist Université de Bordeaux, BPH INSERMU1219, équipe EPICENE, Institut Bergonié
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10.00 am – FLASH POSTER
Chairwoman:
Marion Bouchecareilh
Neutrophil elastase-activatable prodrugs based on an alkoxyamine platform to deliver alkyl radicals cytotoxic to tumor cells
Characterization of the DNA mismatch repair phenotype in sebaceous tumors and analysis of their inflammatory microenvironment.
Immunosuppressive role of mutatedcatenin in hepatocellular carcinoma
Biological and molecular characterization of cancer stem cells in brain metastases from colorectal cancer
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11.00 am – EVOLUTION AND BIODIVERSITY
Chairman:
Bertrand Daignan-Fornier
Cancer cell biodiversity: Mechanisms of coexistence and implications for treatment
◗ Joel Brown, Senior Member of the Departmentof Integrated Mathematical Oncology, Moffitt Cancer Center, Florida.
Evolving cells to decipher adaptive processes
◗ Damien Coudreuse, CNRS researcher, IBGC, Bordeaux
LncRNA expression during myeloid cell differentiation in liver cancer
◗ Domitille Chalopin-Fillot, Post doc, IBGC, Bordeau
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2.00 pm – INVASION AND METASTASIS
Chairs:
Majid Khatib and Violaine Moreau
MiRNA-20a regulates angiogenic process during liver metastasis
◗ Iker Badiola, Assistant professor, Universidad del País Vasco
Regulation of breast cancer stem cell activity in therapy resistance and metastasis
◗ Robert Clarke, Professor, Manchester Breast Centre
APNL/APJ system and first early metastatic events
◗ Majid Khatib, Research director, BRIC, Bordeaux
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4.00 pm – COMPUTATIONAL SCIENCE FOR ONCOLOGY
Chairs:
Macha Nikolski and Clair Poignard
How can mathematical models help in Oncology? Biomarker discovery and in-silico trials
◗ Victor Perez-Garcia, Professor, MOLAB, University of Castilla-La Mancha, Spain
Spatial and temporal tumor heterogeneity
◗ Benjamin Raphael, Professor, Lewis-Sigler Institute,Princeton University
Mathematical modeling and data assimilation in tumor growth. Some illustrative examples
◗ Annabelle Collin, Associate Professor, Bordeaux INP
Gedepir, a package for Gene Expression DEconvolution IN R
◗ Slim Karkar, Bordeaux Bioinformatics Center
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6.00 pm to 7.00 pm – GENERAL PUBLIC CONFERENCE :
ROUND TABLE (in French) Qui définit les priorités de la recherche : les patients ou les chercheurs ?
Animated by Yoann Frontout, journalist
◗ Sabine Dutheil, Patient
◗ Béatrice Jacques, Lecturer in sociology, University of Bordeaux
◗ Cyril Sarrauste, Patient
◗ Philippe Souque, Caregiver
◗ Julie Déchanet-Merville, Director of the research laboratory ImmunoConcEpT
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FRIDAY 13th JANUARY
8.00 am – WELCOMING
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8.30 am – CLINICAL AND BIOLOGICAL SPECIFICITIES OF CANCER IN OLDER PATIENTS
Chairs:
Damien Coudreuse and Murielle Mathonnet
Senescence Immune Checkpoints (SIC) : a paradigm shift in Aging and Cancer ?
◗ Julien Cherfils, CRCN CNRS, IRCAN, Nice
In vivo impact of aging on hematopoietic stem cell function
◗ Catherine Sawai, CRCN Inserm ATIP Avenir , BRIC, Bordeaux
Psychological resilience in older couples: illustration in the context of cancer
◗ Valérie Bergua, Maître de conference en psychogérontologie, BPH, Université de Bordeaux
Impact of cardiovascular comorbidities on bevacizumab effectiveness and safety in older patients with metastatic colorectal cancer
◗ Pernelle Noize, Pharmacien spécialisé en pharmaco-épidémiologie, CHU de Bordeaux, BPH,
Université de Bordeaux
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10.00 am – FLASH POSTER
Chairman:
Pierre Soubeyran
Repression of protein maturation inhibits pd-1 expression and enhances tumor clearance and tils: virtual ligand screen-ing and drug repurposing approach
D analysis of invadopodia formation : Implication of the Cx43 protein in the invasive process of human glioblastoma cells
Revealing the link between cell volume and evolution
Activation of the Pro-Apoptotic Death Receptor 5 by Multivalent Agonist Peptides combined or not with
recombinant TRAIL
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11.00 am – CANCER STEM CELLS
Chairs:
Fabrice Lalloué and Valérie Coronas
Microenvironmental regulation of cancer stem cells in glioblastoma
◗ Luca Persano, Assistant Professor, Department of Women’s and Children’s Health, University of Padova, Italy
Alteration of the BMP signaling in stem cells and their niche: cancer initiation and environmental pollutant
◗ Véronique Maguer-Satta, CNRS research director, CRCL, Lyon
Role of calcium channels in glioblastoma stem cells
◗ Valérie Coronas, University professor, 4CS, Poitiers
A new way to identify CSCs
◗ Barbara Bessette, Assistant professor, CAPTuR, Limoges
Connected tumor cells make glioblastoma stronger: from microtubes to metabolic symbiosos
◗ Thomas Daubon, CNRS researcher,
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2.00 pm – INNOVATIVE TECHNOLOGIES FOR ONCOLOGY
Chairs: Jean-Luc Feugeas and Elif Hindié
Vectorized internal radiation therapy
◗ Elif Hindié, PU-PH, Biophysics and Nuclear Medicine, Nuclear Medicine Service, University Hospital Centre Bordeaux
Nuclear imaging and targeted radionuclide therapy: current state at Bordeaux and perspectives
◗ Clément Morgat, MCU PH, Radiopharmacy, UMR5287, INCIA (Institut de Neurosciences Cognitives et Intégratives d’Aquitaine), Bordeaux
Photodynamic cancer gene therapy
◗ Sandrine Dabernat, PU-PH, Professor in cell biology, hospital biologist, Biotherapies Genetics and Oncology (BioGO), BRIC, Bordeaux
PhotoDynamic Therapy: an adjuvant anti-cancer therapy
◗ Bertrand Liagre, Professor of Biochemistry & Molecular Biology, Head of Department at Faculté
de Pharmacie, University of Limoges
Artificial intelligence
◗ Baudouin Denis de Senneville, CNRS, Mathematics, CNRS, UMR5251, Mathematical Institute of Bordeaux
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4.00 pm – NEW HORIZONS IN ONCO-IMMUNOLOGY
Chairs:
Vanja Sisirak and Maya Saleh
The dual role of inflammation in cancer immunity
◗ Santiago Zelenay, Tenured Group leader, Cancer research UK, Manchester Institute
Macrophage subsets and T cell immunity in Breast Cancer
◗ Julie Helft, Inserm researcher, Cochin Institute, Paris
Role of extracellular DNASEs inter control of therapy induced anti-tumor immunity
◗ Vanja Sisirak, CNRS researcher, ImmunoConcept, Bordeaux
Integrative analysis of hepatocellular carcinoma by single-cell RNA sequencing identifies the TREM1+ regulatory myeloid cells as a target for immunotherapy
◗ Maya Saleh, Researcher, ImmunoConcept, Bordeaux
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5.30 pm – AWARD CEREMONY AND CONCLUSION
◗ Pierre Soubeyran, Director of the Oncosphère Nouvelle-Aquitaine
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